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Polyvinylpyrrolidone (Pharmaceutical Grade)

 Product Name: Polyvinylpyrrolidone

 Chemical Description: Homopolymer of 1-Vinly-2-Pyrrolidone,Polyvinylpyrrolidone

 INCI/CTFA: PVP

 Pharmacopeia Name: Povidone

 CAS NO.: 9003-39-8

 

Product Properties: Povidone is a hygroscopic polymer ,supplied in white or creamy white powder or flakes, ranging from low to high viscosity & low to high molecular weight, which characterized by K Value.It’s easily soluble in water and many other organic solvents, with excellent hygroscopisty, film-forming, adhesive, chemical stability and toxicological safeness characters.

 

Applications: Povidone is one of the most important excipient in the worldwide for pharmaceutical industry, whatever for human health care products and animal health care products. It’s more and more used as:1)Binder for tables,capsule,2)Sugar coatings and films,3)Thickening agent,4)Solubility Improver for poorly soluble drugs,5)Bioavailability Enhancer for drug’s active ingredients,6)Pore-forming for membrane products.

 

Specifications:

Product

Povidone   K15

Povidone   K17

Povidone   K25

Povidone   K30

Povidone   K60

Povidone   K90

Appearance

White or   yellowish-white,hygroscopic powder or flakes

Solubility

Freely   soluble in water,in ethano(96%) and in methanol,very slightly soluble in   acetone.

Appearance   of Solution

Clearly   and not moren intensely coloured than reference solution B6,BY6 or   R6

Identifications

Meet ID   Tests

pH   Value(5% in aqueous solution)

3.0-5.0

3.0-5.0

3.0-5.0

3.0-5.0

4.0-7.0

4.0-7.0

Viscosity(Expressed   as K Value)

12.75-17.25

15.3-18.36

22.5-27.0

27.0-32.4

54.0-64.8

81.0-97.2

Adehydes(Expressed   as Acetaldehyde)

500 ppm   max.

500 ppm   max.

500 ppm   max.

500 ppm   max.

500 ppm   max.

500 ppm   max.

Peroxides(Expressed   as H2O2)

400ppm   max.

400 ppm max

400 ppm   max

400 ppm   max

400 ppm   max

400 ppm   max

Formic   Acid

0.5% max.

0.5% max.

0.5% max.

0.5% max.

0.5% max.

0.5% max.

Hydrazine

1ppm max.

1ppm max.

1ppm max.

1ppm max.

1ppm max.

1ppm max.

 N-Vinylpyrrolidone

(Impurity   A)

USP26

1000 ppm   max.

1000 ppm   max.

1000 ppm   max.

1000 ppm   max.

1000 ppm   max.

1000 ppm   max.

Current   USP/EP/BP

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

2-Pyrrolidone(Impurity   B)

3.0% max.

3.0% max.

3.0% max.

3.0% max.

3.0% max.

3.0% max.

Heavy   Metals(as Pb)

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

10 ppm   max.

Water

5.0% max.

5.0% max.

5.0% max.

5.0% max.

5.0% max.

5.0% max.

Sulphated   Ash

0.1% max.

0.1% max.

0.1% max.

0.1% max.

0.1% max.

0.1% max.

Nitrogen   Content

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%


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CONTACT US

  • Fax: +86-731-84421482
  • E-mail: sinogreat@sinogreat.cn
  • Tel: +86-731-84427351
  • Add: RM. 2010, Tian xin cheng (South) 154 Jianxiang South Road, Changsha, Hunan, 410005, China.
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